In Vitro Maturation (IVM)

In Vitro Maturation (IVM)

What is IVM?

In-Vitro Maturation is a safe unique alternative to IVF with more than 5000 healthy IVM babies born worldwide. Instead of requiring women to take hormones, the immature and undeveloped eggs are removed and developed outside the body. Once developed, the mature eggs are then fertilized in the lab and grow to be healthy embryos. Using IVM, women can create multiple viable embryos without using high doses of injectable hormones, limiting side effects, lowering the risk of overstimulation, and eliminating the inconvenience of taking multiple injections. 

In contrast to many IVF Centers, we do not discard immature eggs. Instead, if immature oocytes are obtained at egg retrieval, our embryologists will mature those eggs in our labs, providing our patients with a better chance of getting pregnant.

How does IVM work?

A doctor will surgically collect the patient’s immature or underdeveloped eggs with little to no ovarian stimulation. The immature eggs are then placed in cell culture, sent to our lab and stimulated with hormones until they reach maturity. Generally, Intracytoplasmic Sperm Injection (ICSI) is used to manually fertilize the matured eggs with the sperm sample. Once the eggs are fertilized, the doctor will perform a minor surgical procedure to insert the embryos into the perspective patient.

Who can benefit from IVM?

  • Women who want to take fewer medications when completing the IVF process
  • Women with Polycystic Ovarian Syndrome (PCOS)
  • Women in remission or recovery from hormone-sensitive cancers, such as breast cancer
  • Women with a high risk of Ovarian Hyperstimulation Syndrome (OHSS)
  • Women who have had severe side effects from hormonal medications


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