Recurrent Miscarriage is one of the most devastating diagnoses where a woman has no issues getting pregnant but is unable to keep a pregnancy. Overall, approximately 12 to 15% of clinically recognized pregnancies end in spontaneous miscarriage between 4 and 20 weeks of gestation. About 50 to 75% of miscarriages are the result of chromosomal abnormalities in the embryo and occur by chance.
Reproductive aging in women is associated with an increased risk of miscarriage because of the increase of oocyte chromosomal abnormality as a woman ages. It is part of the biological clock, which also explains why fertility decreases with age while miscarriage increases with age. To battle this occurrence, a patient must understand the strategy of how to beat the odds.
With a highly advanced laboratory and skilled embryologists, a combination of in-vitro fertilization with pre-genetic diagnosis can help increase the odds of getting pregnant with a normal embryo.
However, creating a normal embryo is only one aspect of the treatment. It is very important not to neglect other factors that can also cause miscarriage. Uterine abnormalities, immunological factors, inherited thrombophilias, thyroid dysregulation, and environmental or infectious factors are other mechanisms that can also cause early pregnancy loss. As a result, not all patients with early pregnancy loss need IVF treatments because sometimes there can be factors other than the embryo itself causing the miscarriage. Listening to a woman’s history and individualizing her treatment are absolutely crucial and necessary to attempt preventing a woman from having another miscarriage.