Dr. Ralf Zimmermann comes from an accomplished background in reproductive endocrinology and assisted reproductive technologies (ART), with a special interest in the psychological factors of infertility treatment.  Having completed residencies at Yale University in Obstetrics & Gynecology as well as Psychiatry along with a fellowship at the Mayo Clinic, Dr. Zimmermann brings a unique psychological perspective to the table when working to best meet each of his patient’s needs.

In a rich and varied clinical as well as academic experience from more than twenty years on the faculty at Columbia University’s Division of Reproductive Endocrinology and Infertility, his work is informed by a depth of understanding brought about by rigorous scientific investigation, a commitment to clinical excellence and a high degree of attunement to the stresses that any patient undergoing treatment may be facing, either with their respective partner or as a patient seeking to address infertility issues without a partner. During his tenure at Columbia, he was made director of oncofertility and was particularly interested in establishing treatment protocols for cancer patients to ensure the most effective approaches for preserving future possibilities for conception.

As part of his teaching and supervising of fellows and medical students, he felt privileged to hold the position of Director of the Audobon Clinic of Reproductive Medicine, founded by Columbia University to provide services to low income patients.  Originally from Germany, Dr. Zimmermann received his Doctor of Medicine from the University of Hamburg and is fluent in German, Spanish and French, accommodating many European patients in need of egg donation or other services that are not as readily available outside of the U.S.

BIBLIOGRAPHY & PRESENTATIONS

              1. Douglas NC, Zimmermann RC, Qian KT, Sullivan-Pyke CS, Sauer MV, Kitajewski J, Shawber CJ. VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment Vascular Cell 2014; 6:16.
              1. Garcia-Pascual C, Ferrero H, Zimmermann RC, Simon C, Pellicer A, Gomez R. Inhibition of Delta-like 4 mediated signaling induces abortion in mice due to deregulation of decidual angiogenesis. Placenta 2014; 35:501-508.
              1. Garcia-Pascual C*, Zimmermann RC*, Ferrero H, Shawber C, Kitajewski J, Simon C, Pellicer A, Gomez R (* equal contribution). Delta-like ligand 4 regulates vascular endothelial growth factor receptor 2-driven luteal angiogenesis through induction of a tip/stalk phenotype in proliferating endothelial cells. Fertil Steril 2013; 100:1768-1776.
              1. Jovanovic V*, Sauer CM*, Shawber CJ, Gomez R, Wang X,, Sauer MV, Kitajewski J, Zimmermann RC (* equal contribution). Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on Notch receptor signaling not involving Delta-like-ligand 4 (Dll4). Reprod Biol Endocrinol 2013; 11:43-50.
              1. Ferrero H, Delgado-Rosas F, Garcia-Pascual C, Monterde M, Zimmermann RC, Simon C, Pellicer A, Gomez R. Efficiency and purity provided by the existing methods for the isolation of luteinized granulose cells : a comparative study. Hum Reprod 2012; 27:1781-1789.
              1. Gomez R, Ferrero H, Delgado-Rosas F, Gaytan M, Morales C, Zimmermann RC, Simon C, Gaytan F, Pellicer A. Evidence for the existence of a low dopaminergic tone in polycystic ovarian syndrome: implications for OHSS development and treatment. J Clin Endocrinol Metab 2011; 96:2484-2492.
              1. Westhof G, Deerberg JC, Schad W, Zimmermann RC, Hatzman H. Do macromorphic features of the human placenta influence somatic and psychomotor development of the newborn and early infant? A historical question revisited. Gynecol Obstet Invest 2010; 69:251-259.
              1. Schiermeier S, Reinhard J, Hatzman H, Zimmermann RC, Westhof G. Fetal short-term variation during labor: a non-invasive alternative to fetal scalp ph measurements? J Perinat Medicine 2009; 37:529-533.
              1. Douglas NC, Tang H, Gomez R, Pytowski B, Hicklin DJ, Sauer CM, Kitajewski J, Sauer MV, Zimmermann RC. Vascular endothelial growth factor receptor 2 (VEGFR-2) functions to promote uterine decidual angiogenesis during early pregnancy in the mouse. Endocrinology 2009; 150:3845-3854.
              1. Gomez R, Gonzalez-Izquierdo M, Zimmermann RC, Novella-Maestre E, Alonso-Muriel I, Sanchez-Criado J, Remohi J, Simon C, Pellicer A. Low-dose dopamine administration blocked vascular endothelial growth factor (VEGF)-mediated vascular hyperpermeabiliy without altering VEGF receptor 2-dependent luteal angiogenesis in a rat ovarian hyperstimulation model. Endocrinology 2006; 147:5400-5411.
              1. Westhof G, Olbrecht M, Wolff M, Schiermeier S, Zimmermann RC, Hatzman W. Testing of functional integrity of p53 protein in primary breast cancer by a rapid quantitative p53-p21 doubleassay may improve the clinical value of p53. Tumor Biol 2006; 27:252-256.
              1. Vorontchikhina MA, Zimmermann RC, Shawber CJ, Tang H, Kitajewski J. Unique pattern Of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation. Gene Exp Patterns 2005; 5:701-709 .
              1. Nakhuda G, Zimmermann RC, Bohlen P, Liao F, Sauer MV, Kitajewski J. Inhibition of vascular endothelial cell (VE)-specific adhesion molecule VE-cadherin blocks gondotropin-dependent folliculogenesis and corpus luteum formation and angiogenesis. Endocrinology 2005; 146:1053-1059 (on the cover of Endocrinology).
              1. Pauli SA, Tang H, Wang J, Bohlen P, Prosser R, Sauer MV, Kitajewski J, Zimmermann RC. The vascular endothelial growth factor (VEGF)/VEGF receptor 2 pathway is critical for bloodvessel survival in corpora lutea of pregnancy in the rodent. Endocrinology 2005; 146:1301-1311.

 

              1. Zimmermann RC, Hartman T, Kavic S, Pauli SA, Bohlen P, Sauer MV, Kitajewski J. Vascular endothelial growth factor receptor 2 mediated angiogenesis is essential for gonadotropin-dependent follicle development. J Clin Invest 2003; 112:659-669.

 

              1. Zimmermann RC, Xiao E, Bohlen P, Ferin M. Administration of antivascular endothelial growth factor receptor 2 antibody in the early follicular phase delays follicular selection and development in the rhesus monkey. Endocrinology 2002; 143:2496-2502.

 

              1. Zimmermann RC, Hartman T, Husami N, Bohlen P, Sauer MV, Kitajewski J. Preovulatory treatment of mice with anti-VEGF receptor 2 antibody inhibits angiogenesis in corpora lutea . Microvasc Res 2001; 62:15-25.
              1. Zimmermann RC, Krahn L, Klee GG, Ditkoff EC, Ory SJ, Sauer MV. Prolonged inhibition of presynaptic catecholamine synthesis with alpha-methyl-para-tyrosine attenuates the circadian rhythm of human TSH secretion. J Soc Gynecol Invest 2001; 8:174-178.

 

              1. Zimmermann RC, Xiao E, Husami N, Sauer MV, Lobo RA, Kitajewski J, Ferin M. Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey . J Clin Endocrinol Metab 2001; 86:768-772.
              1. Lindheim SR, Sauer MV,Carmina E, Chang PL, Zimmerman R, Lobo RA. Circulating Leptin levels during ovulation induction: Relationship to adiposity and ovarian morphology . Fertil Steril 2000; 73:493-498.

 

              1. Krahn L, Lin SC, Klee G,G Lu PY, Ory SG, , Zimmermann RC. The effect of presynaptic catecholamine depletion on 6-hydroxymelatonin sulfate: a double blind study with alpha-methyl-para-tyrosine. Europ Neuropsychopharmacol 1999; 9:61-66.
              1. Zimmermann RC, Krahn L, Rahmanie S, Sauer MV. Prolonged inhibition of presynaptic catecholamine synthesis does not alter leptin secretion in normal weight men and women. Hum Reprod 1998; 13:822-825.
              1. Ditkoff EC, Prosser R, Zimmermann RC, Lindheim S, Sauer MV. The addition of norethindrone acetate to leuprolide acetate for ovarian suppression has no adverse effect on ovarian stimulation. J Assist Reprod 1997; 14:92-96.
              1. Krahn LE, Lu PY, Klee G, Delgado P, Lin SC, Zimmermann RC. Examining serotonin function: A modified technique for rapid tryptophan depletion. Neuropsychopharmacology 1996; 15:325-328.

 

              1. Zimmermann RC, Krahn L, Klee G, Delgado P, Lu PY, Ory SG, Lin SC. The impact of gender on alpha-methyl-para-tyrosine mediated changes in prolactin secretion and 6-hydroxymelatonin sulfate excretion. Psychoneuroendocrinology 1996; 21:469-478.
              1. Zimmermann RC, Krahn L, Klee G, Delgado P, Ory SG, Lin SC. Inhibition of presynaptic catecholamine synthesis with alpha-methyl-para-tyrosine attenuates nocturnal melatonin secretion. J Clin Endocrinol Metab 1994; 79:110-1114.
              1. Delfs TM, Klein S, Fottrell P, Naether OG, Leidenberger FA, Zimmermann RC. 24-h profiles of salivary progesterone. Fertil Steril 1994; 62:960-966.
              1. Delfs T, Baars S, Fock C, Schuhmacher M, Olcese J, Zimmermann RC. Sex steroids do not alter melatonin secretion in the human. Hum Reprod 1994; 9:49-54.
              1. McDougle CJ, Black JE, Malison RT, Zimmermann RC , Kosten TR, Heninger GR, Price LH. Noradrenergic dysregulation during discontinuation of cocaine use in addicts. Arch Gen Psychiatry 1994; 51:713-719.
              1. Laruelle MA, Baldwin RM , Malison RT, Zea-Ponce W, Zogbi SS, Al-Tikriti MS, Sibirska EH, Seibyl JP, Zimmermann RC, Wisnieswki G, Neumeyer JL, Millius RA, Wang S, Smith EO, Roth RH, Charney DS, Hoffer PB, Innis RB. SPECT imaging of dopamine and serotonin transporters with [123] ß -Cit: receptor: pharmacological characterization of brain uptake in non-human primates. Synapse 1993; 13:295-309.
              1. Zimmermann RC, McDougle CJ, Schuhmacher M, Olcese J, Heninger GR, Price LH. Urinary 6-hydroxymelatonin sulfate as a measure of melatonin secretion during acute tryptophan depletion. Psychoneuroendocrinology 1993; 18:567-578.
              1. Zimmermann RC, McDougle CJ, Schuhmacher M, Olcese J, Mason JW, Heninger GR, Price LH. Effects of acute tryptophan depletion on nocturnal melatonin secretion in humans. J Clin Endocrinol Metab 1993; 76:1160-1164.
                    1. Innis RB, Al-Tikriti MS, Zogbi SS, Baldwin RM, Sibirska EH, Laruelle MA, Mallison RT, Seibyl JP, Zimmermann RC, Johnson EW, Smith EO, Charney DS, Heninger GR,Woods SW, Hoffer PB. SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves. J Nucl Med 1991; 32:1754-1761.
                    1. Zimmerman RC, Schröder S, Baars S, Schuhmacher M, Weise HC. Melatonin and the ovulatory luteinizing hormone surge. Fertil Steril 1990; 54:612-618.
              1. Bispink G, Zimmermann R, Weise HC, Leidenberger F. Influence of melatonin on the sleep independent component of prolactin secretion. J Pineal Res 1990; 8:97-106.
              1. Zimmermann RC, Westhof G, Peukert-Adam I, Grunert E, Brändle. Follicular size and steroid secretion of dominant bovine follicles. Zentralblatt Gynäcol 1990; 112:1279-1283.
              1. Zimmermann RC, Westhof G, Hoedemaker M, Grunert E, Brändle . Is follicular fluid steroid content representative of follicular steroid secretion? Hum Reprod 1989; 4:29-32.
              1. Zimmermann RC, Westhof G, Peukert-Adam I Hoedemaker M, Grunert E, Brändle . In-vitro steroid secretion of tertiary atretic bovine follicles in a superfusion system correlated to their histological features. Hum Reprod 1987; 2:457-461.
              1. Zimmerman RC, Wun WS, Tcholakien RK, Rodriguez-Rigau L, Brändle W, Steinberger E. In vitro steroid secretion by intact bovine follicles in a superfusion system. Hormone Metab Res 1985; 17:458-463.

 

              1. Westhof G, Brandle W, Sprotte C, Zimmermann R, Bettendorf G. A clinical study of the treatment of sterility in hyperandrogenic ovarian insufficiency (in German). Geburtshilfe Frauenheilk 1985; 45:449-458.
              1. Zimmermann RC, Bohnet HG, Weise HC, Leidenberger F. Preliminary report about a modified gonnadotropin (human menopausal gonadotropin/human chorionic gonadotropin) in infertile patients with premature luteinization. Fertil Steril 1984; 41:714-718.
              1. Zimmermann R, Soor B, Brändle W, Lehmann F, Weise HC, Bettendorf G. Gonadotropin therapy of female infertility: Analysis 0f 416 cases. Gynecol Obstet Invest 1982; 14:1-18.
              1. Zimmermann R, Soor B, Brändle W, Lehmann F, Weise HC, Bettendorf G. Different aspects of hMG/hCG. Infertility 1981; 4:203-210.

Review Articles

1. Douglas NC, Nakuda GS, Sauer MV, Zimmermann RCAngiogenesis and ovarian function.  Journal für Fertilität und Reproduktion 2005; 15:7-15.

2. Cleary-Goldman J, Nakhuda GS, Zimmermann RC, Sauer MV. The role of factor V Leiden in recurrent pregnancy loss.  J Am Med Women’s Assoc 2003; 58:165-172.

Letter to the editor

1. Zimmermann RCCytogenetic consequences of hyperstimulation.  Fertil Steril 1991; 56:373-374.

2. Zimmermann RC. Melatonin in health and disease (response). Fertil Steril 56:373

Chapters
01. Zimmermann RC. Biological principles important for reproductive medicine. In: Lobo RA (ed.): Educational review manual in obstetrics and gynecology. Castle Connolly Graduate Medical Publishing, Ltd., New York, 2003.

02. Zimmermann RC. Melatonin. In: Lobo RA (ed.): Treatment of the postmenopausal women. Lippincott-Raven Press, 1999:603.

03. Zimmermann RC. Dysfunctional uterine bleeding. In: DeCherney A (ed.): Hysteroscopy. Obstet Gynecol Clinics of North America 1988. 15:107.

04.  Weise HC, Bispink G, Ruttmann F, Zimmermann RC, Leidenberger F. Buserilin/hMG and hCG in women with corpus luteum insufficiency. In: Brosens I, Jacobs HS, Runnebaum  B (eds.): LHRH-analogues in gynecology, Parthenon Publishing Company, Carnforch, UK, 1990:83

05. Bettendorf G, Brändle W, Weise HC, Zimmermann RC. New aspects in gonadotropin therapy In: Flamigni C, Givens JR (eds.): The gonadotropins. Basic sciences and clinical aspects in females. Academic Press, London, 1982:411 06. Bettendorf G, Brändle W, Sprotte C, Weise HC, Zimmermann RC. Overall results of gonadotropin therapy. In: Insler V, Bettendorf G (eds.): Advances in diagnosis and treatment of infertility. Elsevier, New York, Amsterdam, 1981:33.

Abstracts

              1. Garcia-Pascual C, Zimmermann RC, Ferrero H, Simon C, Pellicer A, Gomez R. Inhibition of Delta-like 4 mediated signaling induces abortion in mice due to deregulation of decidual angiogenesis. 60th Annual Meeting of the Society of Gynecological Investigation, Orlando, Florida, 2013
              1. Garcia-Pascual C, Zimmermann RC, Ferrero H, Simon C, Pellicer A, Gomez R. Inhibition of Delta-like 4 mediated signaling induces abortion in mice due to deregulation of decidual angiogenesis. 28th Annual Meeting of the European Society of Human Reproduction, Turkey, 2012.
              1. Garcia-Pascual C, Zimmermann RC, Ferrero H, Simon C, Pellicer A, Gomez R. The role of angiogenesis specific Notch in corpora lutea formation. 27th Annual Meeting of the European Society of Human Reproduction (ESHRE). Stockholm, Sweden, 2011.
              1. Brian Levine, Jovanovic V, Sauer CM, Shawber CJ, Gomez R, Wang X, Sauer MV, Kitajewski J, Zimmermann RC. Role of Notch in gonadotropin-dependent folliculogenesis in the rodent. 58th Annual Meeting of the Society of Gynecological Investigation, Miami, Florida, 2011.
              1. Gomez R, Jovanovic V, Sauer CM, Shawber CJ, Wang X, Sauer MV, Kitajewski J, Zimmermann RC. Notch signaling regulates sprouting angiogenesis in corpora lutea through tip cells and stalk cells. 26th Annual Meeting of the European Society of Human Reproduction, Rome, Italy, 2010.
              1. Jovanovic V, Gomez R, V, Shawber CJ, Sauer MV, Kitajewski J, Zimmermann RC. Assembly of mature vasculature during gonadotropin-dependent folliculogenesis requires activated Notch. 26th Annual Meeting of European Society of Human Reproduction, Rome, Italy, 2010.
              1. Gomez R, Jovanovic V, Sauer CM, Shawber CJ, Sauer MV, Kitajewski J, Zimmermann RC. Efficacy of vitrification vs. slow cooling of human zygotes: interim results of a RCT. 26th Annual Meeting of European Society of Human Reproduction, Rome, Italy, 2010.
              1. Sauer MV, Kort D, GS, Wangt X, Sauer MV, Kitajewski J, Zimmermann RC, Blockage of Notch signaling inhibits follicle development in the rodent. Meeting of the Society for Gynecologic Investigation. Glasgow, Scotland, 2009.
              1. Douglas NC, Tang H, Gomez R, V, Pytowski B, Hicklin DJ, Kitajewski J, Sauer MV, J Zimmermann RC. Inactivation of VEGR receptor 2, but not VEGFR03 or VEGFR-1 during the peri-implantation period prevents normal pregnancy development in the rodent through disruption of uterine angiogenesis. 55th Meeting of the Society for Gynecologic Investigation. San Diego, CA, 2008.
              1. Douglas NC, Tang H, Gomez R, V, Pytowski B, Sauer MV, J Zimmermann RC. VEGF receptor 2 (VEGFR-2) and VEGFR-3 mediate peri-implantation uterine angiogenesis during early pregnancy development. 63rd Annual Meeting of the American Society of Reproductive medicine. Washington, DC, 2007.
              1. Douglas NC, Tang H, Gomez R, V, Pytowski B, Sauer MV, J Zimmermann RC. Blockage of the VEGF-C/VEGF receptor 3 pathway disrupts early pregnancy development in the rodent. 62nd Annual Meeting of the American Society of Reproductive medicine. New Orleans, LA, 2006.
              1. Zimmermann RC, Xiao E, Bohlen P, Sauer MV,Ferin M. The preovulatory follicle requires signaling of vascular endothelial growth factor (VEGF) through VEGF receptor 2 (VEGFR-2) for normal functioning in the non-human primate. Conjoint Annual Meeting of the American Society of Reproductive Medicine/Canadian Fertility and Andrology Society. Montreal, Canada, 2005.
              1. Mendonca E, Tang H, Cha W, Bohlen P, Sauer MV, Zimmermann RC.Vascular endothelial growth factor (VEGF) receptor 1 (VEGFR-1) and the VEGF binding protein (extracellular domain of VEGFR-1; s-flt) are involved in regulating ovarian availability of VEGF for folliculogenesis in the rodent. Conjoint Annual Meeting of the American Society of Reproductive Medicine/Canadian Fertility and Andrology Society. Montreal, Canada, 2005.
              1. Tang HY, Cha W, GS, Bohlen P, Sauer MV, Kitajewski J, Zimmermann RC, Inhibition of VEGF receptor 2 causes loss of endothelial cells via a non-apoptotic mechanism in corpora lutea (CL) of pregnant mice. 52nd Meeting of the Society for Gynecologic Investigation. Los Angeles, CA, 2005.
              1. Chu MC, Nakhuda GS, Zimmermann RC, Bohlen P, Liao F, Sauer MV, Kitajewski J. Short-term systemic administration of VEGF induces angiogenesis in immature follicles of prepubertal hypophysectomized mice. 51st Meeting of the Society for Gynecologic Investigation. Houston, TX, 2004.
              1. Vorontchikhina MA, Nakhuda GS, Zimmermann RC, Sauer MV, Kitajewski J. Expression analysis of Notch ligands in follicular, luteal and pregnancy ovaries in mice compared to vascular expressionUnique pattern. 51st Meeting of the Society for Gynecologic Investigation. Houston, TX, 2004.
              1. Pauli SA, Wang J, Bohlen P Sauer MV, Zimmermann RC Blocking of the VEGF/VEGF receptor 2 pathway in the pregnant mouse uterus does not disrupt pre- or post-implantation pregnancy development. 51st Meeting of the Society for Gynecologic Investigation. Houston, TX, 2004.
              1. Nakhuda GS, Chu MC, Liao F, Bohlen P,Sauer MV, Zimmermann RC. Anti-VE cadherin antibodies in contrast to anti-VEGF receptor 2 antibodies do not block early pregnancy development in mice. 51st Meeting of the Society for Gynecologic Investigation. Houston, TX, 2004.
              1. Nakhuda G, Pauli SA, Liao F, Bohlen P Sauer MV, Zimmermann RC. Inhibition of vascular endothelial cell (VE)-specific adhesion molecule VE-cadherin blocks gondotropin-dependent folliculogenesis and corpus luteum formation and angiogenesis. 57th Annual Meeting of the American Society of Reproductive medicine. San Antonio, TX, 2003.
              1. Pauli SA, Wang J, Chu MC, Bohlen P, Sauer MV, Zimmermann RC. Vascular endothelial growth factor (VEGF)/VEGF receptor 2 pathway is critical for normal function of corpora lutea of pregnancy, but not for early pregnancy development. 57th Annual Meeting of the American Society of Reproductive medicine. San Antonio, TX, 2003.

 

              1. Mendonca E, Vorontchikhina MA, Bohlen P, Sauer MV, Kitajewski J Zimmermann RC. Follicular and corpus luteum angiogenesis does not involve recruitment of bone marrow derived endothelial progenitor cells through activated VEGF receptor 1. 57th Annual Meeting of the American Society of Reproductive medicine. San Antonio, TX, 2003.
              1. Wang J, Pauli SA, Kavic SM, Bohlen P, Kitajewski J, Posser R, Crumb K, Sauer MV, Zimmermann RC. Preimplantation administration of anti-VEGF receptor 2 antibody disrupts post-implantation pregnancy in mice. 18th Annual Meeting of European Society of Human Reproduction (ESHRE), Madrid, Spain, 2003.

 

              1. Zimmermann RC, Hartman T, Mendoca H, Bohlen P, Kitajewski J, Ferin M, Sauer MV. Follicular angiogenesis is dependent on VEGF acting through VEGF receptor 2 but not VEGF receptor 1. NICHD/WRHR Scholar’s Research Symposium. Bethesda, ML, 2003.
              1. Villella JA, Zimmermann RC, Zhang Q, , Rudge JS, Hylton D, Smith DH, Chambers J, Kitajewski J. Vascular endothelial growth factor levels in plasma and cysts do not correlate. 50th Meeting of the Society for Gynecologic Investigation. Washington, DC, 2003.

 

              1. Zimmermann RC, Pauli SA, Sauer MV, Bohlen P, Kitajewski J. A single injection of anti-VEGF-R2 antibody on pregnancy day 6 disrupts embryonic development in mice. 50th Meeting of the Society for Gynecologic Investigation. Washington, DC, 2003.

 

              1. Zimmermann RC, Hartman T, Kavic SM, Bohlen P, Sauer MV, Kitajewski J. Angiogenesis is an absolute requirement for the development of mature, antral follicles.18th Annual Meeting of European Society of Human Reproduction (ESHRE), Vienna, Austria, 2002.

 

              1. Zimmermann RC, Xiao E, Bohlen P, Ferin M. Blockage of angiogenesis in the early follicular phase delays follicular selection and development in the rhesus monkey. 84th Annual Meeting of the Endocrine Society, San Francisco, CA, 2002.

 

              1. Zimmermann RC, Hartman T, Kavic SM, Bohlen P, Sauer MV, Kitajewski J. Devleopment of mature, preovulatory follicles is angiogenesis dependent process. 57th Annual Meeting of the American Society of Reproductive medicine. Orlando, Fl, 2001.

 

              1. Zimmermann RC, Kavic SM, Bohlen P, Sauer MV, Kitajewski J. A single preovulatory dose of anti-VEGF-R2 antibody inhibits angiogenesis in murine corpora lutea. 47th Meeting of the Society for Gynecologic Investigation. Toronto, Canada, 2001.

 

              1. Zimmermann RC, Xiao E, Husami N, Sauer MV, Lobo RA, Kitajewski J, Ferin M. Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey . 82nd Annual Meeting of the Endocrine Society, Toronto, Canada, 2000.

 

              1. Zimmermann RC, Lindheim SR, Sauer MV, Kitajewski J. Comparison of free and total vascular endothelial growth factor (VEGF) in serum in the non-pregnant and pregnant state in the same patient. 47th Meeting of the Society for Gynecologic Investigation. Chicago, Ill, 2000.

 

              1. Zimmermann RC, Kavic SM, Bohlen P, Sauer MV, Kitajewski J. Anti-Flk1 antibodies attenuate estradiol (E2) induced endometrial development in an immature mouse model: preliminary results. 47th Meeting of the Society for Gynecologic Investigation. Chicago, Ill, 2000.

 

              1. Zimmermann RC, Vo T, Leung L, Bohlen P, Sauer M. Anti-Flk1 antibodies block corpus luteum formation in immature mice treated with PMSG/hCG . 55th Annual Meeting of the American Society of Reproductive medicine. Toronto, Canada, 1999.
              1. Zimmermann RC, Julius MA, Sauer MV, Kitajewski J. Wnt-1 increases cell-cell adhesiveness in mouse 15P-1 sertoli cells . 45th Meeting of the Society for Gynecologic Investigation. Atlanta, Georgia, 1998.
              1. Rosenthal JL, Zimmermann RC, Sauer MV. The desire for childbearing in women of advanced maternal age: Findings in a donor oocyte program. 53rd Annual Meeting of the American Society of Reproductive Medicine. Cincinnati, OH, 1997.

 

              1. Zimmermann RC, Rahmanie S, Krahn L, Ferin M,Sauer MV. Inhibition of norepinehrine synthesis catecholamine synthesis with alpha-methyl-para-tyrosine does not alter leptin secretion. 53rd Annual Meeting of the American Society of Reproductive Medicine. Cincinnati, OH, 1997.

 

              1. Zimmermann RC, Julius MA, Sauer MV, Kitajewski J. Wnt-1 increases the pool of cytosolic beta-catenin in mouse 15P-1 Sertoli cells . XIV Testis Workshop: Germ Cell Development, Division, Disruption and Death. 1997.

 

 

              1. Zimmermann RC, Julius MA, Sauer MV, Kitajewski J. Wnt-1 induces morphological changes in mouse 15P-1 sertoli cells . 44th Meeting of the Society for Gynecologic Investigation. San Diego, CA, 1997.
              1. Zimmermann RC Wu JQ, McGee S, Kitajewski J. Expression of Wnt genes in the testis. 52nd Annual Meeting of the American Society of Reproductive Medicine. Boston, MS, 1996.
              1. Lu PY, Krahn L, Lin SC, Klee G, Ory SG, , Zimmermann RC. Ovarian androgen production is not affected by sympathetic nervous system (SNS) suppression with alpha-methyl-para-tyrosine (AMPT). 51st Annual Meeting of the American Fertility Society. Seattle, Washington State,1996.

 

              1. Zimmermann RC, Krahn L, Klee G, Ory SG, Lin SC. Alpha-methyl-para-tyrosine (AMPT) induced changes in noradrenergic transmission do not induce symptoms encountered in premenstrual syndrome (PMS) in the early follicular phase of the menstrual cycle in healthy women. 50th Annual Meeting of the American Fertility Society. San Antonio, Texas,1995.

 

              1. Zimmermann RC, Krahn L, Klee G, Ory SG, Lin SC. Effect of alpha-methyl-para-tyrosine on melatonin secretion in humans. 41th Meeting of the Society for Gynecologic Investigation. Chicago, Illinois, 1994.

 

              1. Zimmermann RC, Krahn L, Klee G, Ory SG, Lin SC. The effect on alpha-methyl-para-tyrosine on urinary 6-hydroxymelatonin excretion in humans. 38. Symposium der Deutschen Gesellschaft für Endokrinologie. Münster, Germany, 1993.
              1. Zimmermann RC, McDougle CJ, Olcese J, Schuhmacher M, Svoboda J, Heninger GR, Price LH.Quantitative relationship netween plasma melatonin secretion, 6-hydroxymelatonin sulfate excretion and lowering of plasma tryptophan levels. 49th Annual Meeting of the American Fertility Society. Montreal, Canada,1993.

 

              1. Zimmermann RC, Svoboda J, McDougle CJ, Olcese J, Schuhmacher M, Werner R, Heninger GR, Price LH. The effect of acute tryptophan depletion on urinary 6-sulphatoxymelatonin excretion in humans human melatonin secretion. 37. Symposium der Deutschen Gesellschaft für Endokrinologie. Berlin, Germany, 1993.

 

              1. Zimmermann RC, McDougle CJ, Olcese J, Schuhmacher M, Svoboda J, Heninger GR, Price LH. The Effect of acute tryptophan depletion on human melatonin secretion. 47th Annual Meeting of the American Fertility Society. Bona Vista, Florida,1992.

 

              1. Zimmermann RC, Svoboda J, McDougle CJ, Olcese J, Schuhmacher M, , Heninger GR, Price LH. The Effect of acute tryptophan depletion on human melatonin secretion. 36. Symposium der Deutschen Gesellschaft für Endokrinologie. Erlangen, Germany, 1992.
              1. Delfs T, Bispink G, Elsen A, Zimmerman RC. Does dopamine mediate the intaction between melatonin and prolactin secretion. 47th Annual Meeting of the American Fertility Society. Orlando, Florida,1991.
              1. Delfs T, Zimmermann RC, Baars S, Schuhmacher M, Leidenberger F. Plasma melatonin levels and urinary melatonin and sulphatoxymelatonin excretion during pregnancy. II. Joint ESCO-ESHRE Meeting. Milano, Italy, 1990.

 

              1. Zimmermann RC, Delfs T, Baars S, Schuhmacher M, Leidenberger F. Plasma melatonin levels in the spontaneous female cycle, during the intake of oral contraceptives, under treatment with gonadotropins, and in early pregnancy. II. Joint ESCO-ESHRE Meeting. Milano, Italy, 1990.
              1. Klein S, Delfs T, Zimmerman RC, Weise HC. Pulsatile progesterone secretion in plasma and saliva in the midluteal phase. 34. Symposium der Deutschen Gesellschaft für Endokrinologie. Hannover, Germany, 1990.

 

              1. Zimmerman RC, Schröder S, Baars S, Schuhmacher M, Weise HC. Melatonin and the ovulation. 45th Annual Meeting of the American Fertility Society. San Francisco, California,1989.
              1. Weise HC, Naether O, Fischer R, Berger-Bispink S, Zimmerman RC. Treatment of polycystic ovarian disease (POD) by laparoscopic ovarian cautery. 45th Annual Meeting of the American Fertility Society. San Francisco, California,1989.
              1. Schröder S, Lammers W, Zimmermann RC, Weise HC, Leidenber F. Die klinische Bedeutung der Galaktorrhoe in der perimenopause . 9. Wissenschaftliche Tagung der Deutschen Gesellschaft für Senologie. Hamburg, Germany, 1989.
              1. Schröder S, Kersting A, V, Berger-Bispink S, Zimmermann RC. The frequency of of codominance in consecutive induced ovarian cycles. 5th Annual Meeting of European Society of Human Reproduction (ESHRE), Malmö, Sweden, 1989.

 

              1. Zimmermann RC, Naether O, Fischer R, V, Weise HC. Proerenin-A possible new marker in the diagnosis of polycystic ovarian disease (POD). 5th Annual Meeting of European Society of Human Reproduction (ESHRE), Malmö, Sweden, 1989.

 

              1. Zimmerman RC, Schröder S, Baars S, Weise HC. Melatonin and prolactin during pregnancy. 33. Symposium der Deutschen Gesellschaft für Endokrinologie. Kahrsruhe, Germany, 1986.

 

              1. Zimmermann RC, Westhof G, Hoedemaker M, Grunert E, Brändle W. Size and estradiol secretion of single intact dominant bovine follicles studied in a superfusion system. 35th Meeting of the Society for Gynecologic Investigation. Baltimore, Maryland, 1988.
              1. Corfman R, Zimmermann RC, Grainger D, Roberts KD. A potential role for trypsin inhibitors in endometriosis-associated infertility. 44th Annual Meeting of the American Fertility Society. Atlanta, Georgia,1988.

 

              1. Zimmermann RC, Thatcher S, Corfman R, Pellicer A. Prediction of plasma E2 levels by follicular size in hMG/hCG cycles. 44th Annual Meeting of the American Fertility Society. Atlanta, Georgia,1988.

 

              1. Zimmermann RC, Westhof G, Hoedemaker M, Grunert E, Brändle W. Is ovarian follicular fluid (FF) steroid concentration a good indicator for follicular steroid secretion. Fifth World Congress on in Vitro fertilization and Embryo transfer. 1987.
              1. Westhof G , Zimmermann RC, Brändle W, Hoedemaker M, Grunert E. Stimulation of bovine tertiary follicles with gonadotropins in a superfusion system. 30. Symposium der Deutschen Gesellschaft für Endokrinologie. Munich, Germany, 1986.
              1. Westhof G, Brandle W, Sprotte C, Zimmermann R, Bettendorf G. Treatment of infertile hyperandrogenic women. XI World Congress of Gynecology and Obstetrics. 1985.

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              1. Zimmermann RC, Westhof G , Peukert-Adam I, , Brändle W, Grunert E.Steroid secretion pattern of tertiary atretic bovine follicles in a superfusion system. XI World Congress of Gynecology and Obstetrics. 1985.
              1. Zimmermann RC, Peukert-Adam I, Westhof G, Brändle W, Grunert E. Steroidsekretion von tertiären Rinderfollikeln des Rindes zu verschiedenen Zeiten nach Prostaglandingabe. intakten Rinderfollikeln-eine dynamische Methode zum Studium der Follikelfunktion. Zuchthygiene 19: 105. 1984.
              1. Brändle W, Zimmermann RC, Sprotte C, Bettendorf G. Spontangraviditäten bei Sterilitätspatientinnen. Therapieerfolg? 29. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe. 1983.
              1. Zimmermann RC, Rodriguez-Rigau L, Brändle W, Steinberger E. Superfusion von intakten Rinderfollikeln-eine dynamische Methode zum Studium der Follikelfunktion. 29. Kongress der Deutschen Geselschaft für Gynäkologie und Geburtshilfe. 1979.
              1. Brändle W, Zimmermann RC, Bettendorf G. Prolactin and ovarian dysfunction: Diagnostic and therapeutic results in 567 patients inhibitors in the treatment of ovarian dysfunction. 24. Symposium der Deutschen Gesellschaft für Endokrinologie. Berlin, Germany, 1979.
              1. Bettendorf G, Zimmermann RC, Brändle W. The use of prolactin inhibitors in the treatment of ovarian dysfunction. Symposium on disorders of the hypothalamic-pituitary axis: New possibilities for drug treatment. Moskow, USSR, 1979.
              1. Bettendorf G, Brändle W, J, Zimmermann RC. An evaluation of data in 567 patients with sterility in a one-year period. IX World Congress of European Society of Obstetrics and Gynecology, Tokyo, Japan, 1979.
              1. Weise HC, Zimmermann RC, Brändle W, Leidenberger F, Bettendorf G. Critical analysis of gonadotropin induced ovulation over a 6-year period. Zuchthygiene-Reproduction in Domestic Animals, 1979; 14: 133.
              1. Bettendorf G, Lehman F, Leidenberger F, Zimmermann RC. Human menopausal gonadotropin therapy. American Fertility Society Meeting, 1977.